Fluoxetine
فلوکستین
🧠 Nervous SystemSSRI
Market / country: 🇺🇸 USA
Prozac (US)
🧮 Dose calculator
Major depressive disorder · Regimen source: FDA Fluoxetine · 2.1FDA Fluoxetine · 8.4
- • After 1 week at 10 mg increase to 20 mg; lower-weight children may start and stay at 10 mg. FDA Fluoxetine · 2.1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ MAOI within 14 days; no MAOI within 5 weeks after stopping fluoxetine; linezolid or IV methylene blue. FDA Fluoxetine · 4
Warnings
- • Boxed warning: Increased risk of suicidal thoughts and behavior in children, adolescents and young adults (up to 24 years); monitor closely for clinical worsening. FDA Fluoxetine · WARNING: SUICIDAL THOUGHTS AND BEHAVIORS
Formulations
- 10 mg capsule — capsule 🇺🇸 USA FDA Fluoxetine · 3
- 20 mg capsule — capsule 🇺🇸 USA FDA Fluoxetine · 3
- 40 mg capsule — capsule 🇺🇸 USA FDA Fluoxetine · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Fluoxetine · 8.1
“Risk Summary Based on data from published observational studies, exposure to SSRIs, particularly in the month before delivery, has been associated with a less than 2-fold increase in the risk of postpartum hemorrhage [see Warnings and Precautions (5.7) and Clinical Considerations].”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Fluoxetine · 8.2
“Risk Summary Data from published literature report the presence of fluoxetine and norfluoxetine in human milk (see Data).”
- 👶 ChildrenDangerous / avoid
Boxed warning in the label about children. FDA Fluoxetine · Boxed Warning
“Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Fluoxetine · 8.5
“… significant hyponatremia in elderly patients, who may be at greater risk for this adverse reaction [see Warnings and Precautions (5.9) ] .”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA078619
- DailyMed (FDA label)FDA Fluoxetine
- MedlinePlus (NIH)Fluoxetine
- WHO ATC/DDDN06AB03
- Darooyab (Iran)Fluoxetine
🇮🇷 Registered in Iran Darooyab · G-585/Fluoxetine
Dosage forms with Iranian generic codes, per Darooyab.
- 02051 · FLUOXETINE 20MG/5ML SYRUP · شربت فلوکستین ۲۰ میلیگرم / ۵ میلیلیتر
- 01512 · FLUOXETINE HCL 10MG CAP · کپسول فلوکستین هیدروکلراید ۱۰ میلیگرم
- 00551 · FLUOXETINE HCL 20MG CAP · کپسول فلوکستین هیدروکلراید ۲۰ میلیگرم
- 16338 · FLUOXETINE HCL 20MG TAB · قرص فلوکستین هیدروکلراید ۲۰ میلیگرم
- 52820 · FLUOXETINE (AS HYDROCHLORIDE) CAPSULE, DELAYED RELEASE ORAL 90 mg · کپسول تأخیریرهش فلوکستین (معادل هیدروکلراید) ۹۰ میلیگرم
- 53063 · FLUOXETINE (AS HYDROCHLORIDE) TABLET ORAL 10 mg · قرص فلوکستین (معادل هیدروکلراید) ۱۰ میلیگرم
- 53064 · FLUOXETINE (AS HYDROCHLORIDE) TABLET ORAL 20 mg · قرص فلوکستین (معادل هیدروکلراید) ۲۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Fluoxetine · 3FDA Fluoxetine · 2.1FDA Fluoxetine · 8.4FDA Fluoxetine · 2.2FDA Fluoxetine · 2.3FDA Fluoxetine · 2.4FDA Fluoxetine · 4FDA Fluoxetine · WARNING: SUICIDAL THOUGHTS AND BEHAVIORSFDA Fluoxetine · 8.1FDA Fluoxetine · 8.2FDA Fluoxetine · Boxed WarningFDA Fluoxetine · 8.5FDA Fluoxetine · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-585/Fluoxetine
- Clinical review⚠ Unverified