Phenytoin

🧮 Dose calculator

Epilepsy (complex partial / absence seizures) · Regimen source: FDA Phenytoin ER · 2.1FDA Phenytoin susp · 2.2

• • If controlled on 100 mg tid, 300 mg once daily may be considered (extended capsules only). Serum levels may be needed. Suspension: max 25 mL/day. FDA Phenytoin ER · 2FDA Phenytoin susp · 2.2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Phenytoin ER · 8.1

  “Information on the registry can also be found at the website http://www.aedpregnancyregistry.org/ Risk Summary In humans, prenatal exposure to phenytoin may increase the risks for congenital malformations and other adverse developmental outcomes.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Phenytoin ER · 8.2

  “Risk Summary Phenytoin is secreted in human milk.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Phenytoin ER · 8.4

  “Initially, 5 mg/kg/day in two or three equally divided doses, with subsequent dosage individualized to a maximum of 300 mg daily.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Phenytoin ER · 8.5

  “Phenytoin clearance tends to decrease with increasing age [see Clinical Pharmacology (12.3) ] .”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.